Which white blood cell disorder is characterized by the presence of the Philadelphia chromosome in 90% of cases?
A chronic lymphocytic leukemia (CLL)
B acute lymphocytic leukemia (ALL)
C chronic myelogenous leukemia (CML)
D acute myelogenous leukemia (AML)
E multiple myeloma
Answer: C
Philadelphia Chromosome occurs in CML. ALL occurs in children. AML is associated with Auer rods. Multiple myeloma has Bence-Jones protein. CLL has no clear distinguishing feature except increased lymphocytes.
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